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Sunday, December 1, 2019

Amino Acid Codex Signal Dice


Amino Acids are essentially the Lego's of Life.  There are about 1000 Amino Acids in all, that have been found and artificially added to cells.  But only 22 or proteinogenic.  Usually 20 are exposed to high school biology students.  The elite 22 are directly coded by codons on the mRNA.  Others come about by modification.  Nonetheless these 22 molecules are the animated part of the cell that does much of the work. 

The dots represent the carbon within each Amino Acid.  Except for Proline, Proline is special.  There is always one black sheep in the family.  Likewise there is one Amino Acid that acts differently.  

First of all, a more grounded way to think of Amino Acids is to think of them as Fairy Fibers.  In essence, Fairies are made up of 22 different fibers.  In this analogy Fairies are Proteins.  Thus there are a nearly an infinite number of Fairies that can be made within a cell.  Once a Molecular Fairy is made within a cell it does magic, also known as work.  Some Fairies rearrange chemical bonds with magic wands (active sites), while other Fairies transport materials.  Many Fairies send signals to others, or wear more than one tiara. 

The key is that Fairies in your cells are similar to the Fairies in your cat or the Fairies of a potato.  The Fairies that turn sugar into ATP are similar all across the board from those found in mushrooms to cells of your eye balls.  Remember that Molecular Fairies are made up of amino acids. 

And when they were naming Amino Acids they could have called them Carboxyl Bases.  Or maybe Amino Bases?  Amino-Carboxyl Acid-Bases?  The thing about Amino Acids is that they are both Acids and Bases, kind of like hermaphrodites.  In fact they are called Zwitter Ions, which means Double Gender or Hermaphrodite Ions in German.  So in direct English they are Hermaphroditic Ions, or maybe Gender-Bender Ions, or Inter-Sexed Ions? 




Saturday, November 30, 2019

Stop Sign Codons for Protein Genesis

Street signs are a special kind of vexilloid.  Although they are not made of fabric they convey information in a manner like a flag.  Street signs are even held of the ground like flags.  Instead of poles, they have a standard type big boy erector set kind of 'pole.'

Perhaps the most famous kind of street sign is the stop sign.  Its unique eight sided octagonal shape is distinguished.  In the image above the stop sign motif is combined with bioalchemy.  Bioalchemy is the cool term for biochemistry.

The three standard stop codons are made into street signs: UGA, UAA, and UAG.  Also a mnemonic is added.  UGA's mnemonic is U Get Ata'here.  UAA's mnemonic is U Are Ata'here.  And finally, UAG's is U Are Gone.

Also note the start codon for proteins is AUG, which is like saying "Aye You Guys!"  There is a dated saying like this with PBS's Television Workshop from the late 1970s.  More famously from the Goonies, this was Sloth's catch phrase...sort of.  I think he said Hey but were changing it to Aey, it's a mulligan.

Below is the Elemental Table of Proteinogenic Amino Acids:



Thursday, November 28, 2019

Amino Acid Tyrosine Flag: Y Flag or Tyr

The Tyrosine flag uses the colours orange, light blue, pink, and black.  The orange and cyan stripe along the hoist refer to the number 25.  Reason being orange is coded to 2 and cyan is coded to 5 in colour metrics.  Together these numbers represent the 25th letter of the alphabet, which is also the one letter abbreviation for Tyrosine.

The pink square field indicates that Tyrosine has an alcohol component in its R-Group.  Since oxygen is usually red and hydrogen is white in most models, when you combine those colours they make pink.  The seven black dots indicate that amino acid Y has seven carbons in its R-Group.  And since there are four black dots in the corners of the pink square this indicates that Amino Acid Y has a ring structure.  In fact it is aromatic.

Tyr is the three letter abbreviation.  And Tyr was discovered in 1846 by German chemist Justus von Liebig in cheese.  Although is has an alcohol as a component, you will not get drunk from consuming this amino acid.

Tyrosine gets its name from cheese, since tyri is Greek for cheese.  Thus nick names for this cheese could be: Cheesine, Kraftosine, Velveetisine, Cheddarsine, Quesosine, Formagiosine, Cheezusine, Kasesine (German), Syrsine (Russian), Jabanisine (Arabic), Pomaisine (Vietnamese), Ostsine (Swedish), Sajtosine (Hungarian), Juustosine (Finnish), and Jabinisine (Swahili).

τυροσίνη=Greek for Tyrosine


Amino Acid Tryptophan Flag: W Flag or Trp

Happy Thanksgiving.  It's the most popular amino acid of the them all: Tryptophan.  Today several million Americans will invoke the name of Amino Acid W, better known Tryptophan.  It will be name dropped on the television news today.  Yet, very few will remember that it is only one of 21 other amino acids that will be consumed today.

The flag for Tryptophan uses the colours orange, yellow, white, and blue.  It fills up the square field completely and harmoniously.  There are 9 carbons in the R-Group, thus there are 9 white dots.  The field is blue because the R-Group contains a nitrogen.

Along the hoist is an orange and yellow stripe that refers to one letter abbreviation for this amino acid: W.  Orange is coded to 2 and yellow is coded to 3 in colour metrics, because orange is the 2nd colour and yellow is the 3 colour of the common spectrum.  Together these number make 23 and W is the 23rd letter of the alphabet.

Freddy Hopkins discovered this famous Turkey Day amino acid in 1901.  Fred was from the UK.




Amino Acid Valine Flag: V Flag or Val Flag


The Valine flag uses the colours orange, black and white. The white dots on the black field indicate three carbons make up the functional R-Group.  The dots also illustrate the geometric arrangement of the atoms in the branched V shape.

The orange stripes along the hoist relate to the number 22, because V is the 22nd number.  Reason being, orange is the 2nd colour of the common rainbow.  Thus it reads 2 and 2.  Also black is the assigned contrast indicator.  If the thin black contrast stripe was not present it would appear to be one orange block. 

 Amino Acid V was discovered by wonder biological alchemist Hermann Emil Fischer in the year 1901, Germany.

Valine is an essential ingredient to maintain stemcells that make blood.


Wednesday, November 27, 2019

Amino Acid Selenocystine: U Flag or Sec Flag

The flag for Selenocystine uses the colours orange, red, and black.  The single black dot represents the lone carbon in the R-Group.  The orange and red stripe refer to the Selenocystine's single letter abbreviation: U.  The stripes indicate the number 21 and U is the 21st number of the alphabet.  Red represents 1 and orange represents 2, together they make 21.

The orange field is unique for amino acid flags, since only one R-Group uses this rare transitional element.

Amino Acid U was discovered by a New Yorker, Thressa Stadtman sat the National Institutes of Health. Its discovery dates back to 1954 but name dates to 1959.




Amino Acid Treonine Flag: T Flag or Thr Flag

The flag for Threonine uses the colours orange, black, white, and pink.  It was first discovered in 1936 by an American from South Carolina, William Cumming Rose.

The black and white stripes relate to the one letter abbreviation for Threonine, which is T.  Since the letter T is the 20th letter of the alphabet the colour metric for 20 is used: orange represents one, while white represents zero.

Since this R-Group has two carbons, there are two black dots.  Also the field is pink as to indicate there is an alcohol in the amino acid T.  Pink is used to represent alcohol because in most models oxygen is usually red and hydrogen usually white: together, red with white makes pink.